Dr. Antonia Marazioti is an Assistant Professor in Physiology at the Department of Physiotherapy, University of Peloponnese. She received her bachelor’s in Biology (2001) from the University of Patras and her MSc (2004) and PhD (2007) in Neuroscience from the Crete University School of Medicine. She carried out postdoctoral training in different research laboratories in the fields of Vascular Physiology (2008-2011), Biology of Thoracic Malignancies (2011-2017) and Nanomedicine (2018-2020). In 2020 Dr. Marazioti enrolled as a Research Associate of Department of Pharmacy in collaboration with the FORTH/ICE-HT Institute in Patras, where she developed research strategies for studying molecular physiology aspects of Bone Regeneration (Horizon program 2020-2024). In 2021 Dr. Marazioti was elected Assistant Professor in Physiology in the Department of Physiotherapy, University of Peloponnese. She is a founder member of the Basic Science Laboratory, the Erasmus Coordinator, member of the qualifying exams Committee and member of the Internship Committee of the Department of Physiotherapy.
Dr. Marazioti has published over 35 research publications in peer-reviewed International Journals with >1.500 citations, h-index 16 and mean IF: 6.56, 7 book chapters, over 50 participations in National and International Conferences and has been the recipient of several awards, among which the Research Award by the Hellenic Association for Molecular Cancer Research and a Reserarch award by the European Respiratory Society. Dr. Marazioti has participated in over 10 Research grants, among which 2 ERC grants and 2 Horizon grants. She is a member of Scientific Societies such as American Physiology Society, European Respiratory Society, European Neuroscience Society, Hellenic Society of Physiology, Hellenic Thoracic Society. She has teaching experience in Human Physiology, Pathophysiology, Biology, Pharmacology, Bioethics, Research methodology, Mouse models of human diseases and nanomedicine in drug delivery from 2007 in different Departments and Universities, such as Medical and Pharmacy School of University of Patras, in pre- and post-graduate level. Her current research interests are focused in Cancer Biology, Molecular Pathophysiology of Neurodegenerative diseases and Nanomedicine.
Selected Publications
1. Marazioti A, Krontira AC, Behrend SJ, Giotopoulou GA, Ntaliarda G, Blanquart C, Bayram H, Iliopoulou M, Vreka M, Trassl L, Pepe MAA, Hackl CM, Klotz LV, Weiss SAI, Koch I, Lindner M, Hatz RA, Behr J, Wagner DE, Papadaki H, Antimisiaris SG, Jean D, Deshayes S, Grégoire M, Kayalar Ö, Mortazavi D, Dilege Ş, Tanju S, Erus S, Yavuz Ö, Bulutay P, Fırat P, Psallidas I, Spella M, Giopanou I, Lilis I, Lamort AS, Stathopoulos GT (2022). KRAS signaling in malignant pleural mesothelioma. EMBO Molecular Medicine 13; e13631. doi: 10.15252/emmm.202013631.
2. Marazioti A*, Papadia K, Giannou AD, Stathopoulos GT and Antimisiaris SG (2019). Prolonged retention of liposomes in the pleural cavity of normal mice and high tumor distribution in mice with malignant pleural effusion, after intrapleural injection. International Journal of Nanomedicine 14:3773-3784. *Corresponding author.
3. Marazioti A*, Lilis I, Vreka M, Apostolopoulou H, Kanellakis NI, Agalioti T, Giannou AD, Paris-Jones C, Giotopoulou G, Krontira A, Iliopoulou M, Giopanou I, Iwakura Y, Kardamakis D, Blackwell TS, Spella M and Stathopoulos GT (2018). Myeloid-derived IL-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion. Nature Communications 9(1):672. *Corresponding author
Dr. Marazioti research interests are focused in the study of:
- The biology of Cancer and specifically of thoracic malignancies
- The molecular pathophysiology of Neurodegenerative Diseases and brain diseases
- The development of new therapeutic methods, related both to the identification of new molecular targets and to the use of Nanomedicine technology (targeted drug nanocarriers)
- The molecular pathways activated/inhibited during therapeutic exercise in cancer patients (recent research activity).